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Ibuprofen, in particular, possesses Nf-kB inhibitory activity that may further help reducing excess inflammation/cytokine release in COVID-19 patients ( there is no evidence supporting the association between Ibuprofen and increased risk of severity of COVID-19 ,” a position strengthened by a systematic review appeared 2 months later (Vaja et al.)

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References Azzouni, F., Godoy, A., Li, Y